Anti-NOX4 Polyclonal Antibody (HV319014)

Name: Anti-NOX4 Polyclonal Antibody
Brand: abinScience
SKU: HV319014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
100ug

Número:

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Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HV319014

Descripción

Anti-NOX4 Polyclonal Antibody (HV319014) is a rabbit polyclonal antibody detecting NOX4 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human NOX4 (Gly210-Glu424).

Objetivo

RENOX, NOX4, Renal NAD(P)H-oxidase, NADPH oxidase 4, Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, KOX-1

Purificación

Purified by antigen affinity column.

Número de acceso

Q9NPH5

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

NADPH oxidase 4 (NOX4) is a ~66 kDa protein. NADPH oxidase that catalyzes predominantly the reduction of oxygen to H2O2. Can also catalyze to a smaller extent, the reduction of oxygen to superoxide. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.

1. Mahadev, K. et al. (2004) Molecular and cellular biology 24, 1844-54. PMID: 14966267

2. Park, HS. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 3589-93. PMID: 15356101

3. Martyn, KD. et al. (2006) Cellular signalling 18, 69-82. PMID: 15927447

4. Takac, I. et al. (2011) The Journal of biological chemistry 286, 13304-13. PMID: 21343298

5. Nisimoto, Y. et al. (2014) Biochemistry 53, 5111-20. PMID: 25062272

6. Geiszt, M. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 8010-4. PMID: 10869423

7. Shiose, A. et al. (2001) The Journal of biological chemistry 276, 1417-23. PMID: 11032835

8. Vaquero, EC. et al. (2004) The Journal of biological chemistry 279, 34643-54. PMID: 15155719

9. Pedruzzi, E. et al. (2004) Molecular and cellular biology 24, 10703-17. PMID: 15572675

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-NOX4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo