Anti-NOX4 Polyclonal Antibody (HV319014)

Name: Anti-NOX4 Polyclonal Antibody
Brand: abinScience
SKU: HV319014
Price: 168 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HV319014

説明

Anti-NOX4 Polyclonal Antibody (HV319014) is a rabbit polyclonal antibody detecting NOX4 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human NOX4 (Gly210-Glu424).

ターゲット

RENOX, NOX4, Renal NAD(P)H-oxidase, NADPH oxidase 4, Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, KOX-1

精製

Purified by antigen affinity column.

アクセッション番号

Q9NPH5

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

NADPH oxidase 4 (NOX4) is a ~66 kDa protein. NADPH oxidase that catalyzes predominantly the reduction of oxygen to H2O2. Can also catalyze to a smaller extent, the reduction of oxygen to superoxide. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.

1. Mahadev, K. et al. (2004) Molecular and cellular biology 24, 1844-54. PMID: 14966267

2. Park, HS. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 173, 3589-93. PMID: 15356101

3. Martyn, KD. et al. (2006) Cellular signalling 18, 69-82. PMID: 15927447

4. Takac, I. et al. (2011) The Journal of biological chemistry 286, 13304-13. PMID: 21343298

5. Nisimoto, Y. et al. (2014) Biochemistry 53, 5111-20. PMID: 25062272

6. Geiszt, M. et al. (2000) Proceedings of the National Academy of Sciences of the United States of America 97, 8010-4. PMID: 10869423

7. Shiose, A. et al. (2001) The Journal of biological chemistry 276, 1417-23. PMID: 11032835

8. Vaquero, EC. et al. (2004) The Journal of biological chemistry 279, 34643-54. PMID: 15155719

9. Pedruzzi, E. et al. (2004) Molecular and cellular biology 24, 10703-17. PMID: 15572675

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-NOX4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-NOX4 Polyclonal Antibody (HV319014)

概要

イメージ

参考文献

データシート

SDS

クイックアクセス

お問い合わせ