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Anti-NRL Polyclonal Antibody (HB504014)

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Aperçu
Numéro de catalogueHB504014
Description
Anti-NRL Polyclonal Antibody (HB504014) is a rabbit polyclonal antibody detecting Neural retina-specific leucine zipper protein; NRL; NRL; D14S46E in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant human NRL (Ala2-Leu237).
Cible Neural retina-specific leucine zipper protein; NRL; NRL; D14S46E
Niveau d'endotoxines Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Numéro d'accès P54845, P54846
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Neural retina-specific leucine zipper protein (NRL) is a ~25 kDa protein. Acts as a transcriptional activator which regulates the expression of several rod-specific genes, including RHO and PDE6B. Also functions as a transcriptional coactivator, stimulating transcription mediated by the transcription factor CRX and NR2E3. Binds to the rhodopsin promoter in a sequence-specific manner.

1. Hernan, I. et al. (2012) Clinical genetics 82, 446-52. PMID: 21981118
2. Kanda, A. et al. (2007) Human mutation 28, 589-98. PMID: 17335001
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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