

| Número de catálogo | HV971014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-NUMBL Polyclonal Antibody (HV971014) is a rabbit polyclonal antibody detecting NUMBL in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| Reactividad de especies | Human, Mouse, Rat | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human NUMBL (Ala60-Lys204). | ||||||||
| Objetivo | Numb-R, Numb-like protein, NUMBL, Numb-related protein | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | Q9Y6R0 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Numb-like protein (NUMBL) is a ~64 kDa protein. Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. | ||||||||
| Nota | For research use only. |
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