

| Numéro de catalogue | HV971014 | ||||||||
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| Description |
Anti-NUMBL Polyclonal Antibody (HV971014) is a rabbit polyclonal antibody detecting NUMBL in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human NUMBL (Ala60-Lys204). | ||||||||
| Cible | Numb-R, Numb-like protein, NUMBL, Numb-related protein | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9Y6R0 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Numb-like protein (NUMBL) is a ~64 kDa protein. Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. | ||||||||
| Note | For research use only. |
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