

| Número de catálogo | HW461014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Descripción |
Anti-NUP62 Polyclonal Antibody (HW461014) is a rabbit polyclonal antibody detecting NUP62 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||||||
| Aplicaciones | ELISA, IHC, WB | ||||||||
| Especie huésped | Rabbit | ||||||||
| Clonalidad | Polyclonal | ||||||||
| Isotipo | IgG | ||||||||
| Inmunógeno | E. coli - derived recombinant Human NUP62 (Ala186-Lys432). | ||||||||
| Objetivo | Nuclear pore glycoprotein p62, Nucleoporin Nup62, 62 kDa nucleoporin, NUP62 | ||||||||
| Purificación | Purified by antigen affinity column. | ||||||||
| Número de acceso | P37198 | ||||||||
| Forma | Liquid | ||||||||
| Buffer de almacenamiento | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Fondo | Nuclear pore glycoprotein p62 (NUP62) is a ~53 kDa protein. Essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex. Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation. It might be involved in protein recruitment to the centrosome after nuclear breakdown. 1. Carmo-Fonseca, M. et al. (1991) European journal of cell biology 55, 17-30. PMID: 1915414 2. Hashizume, C. et al. (2013) Cell cycle (Georgetown, Tex.) 12, 3804-16. PMID: 24107630 | ||||||||
| Nota | For research use only. |
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