

| Numéro de catalogue | HW461014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-NUP62 Polyclonal Antibody (HW461014) is a rabbit polyclonal antibody detecting NUP62 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human NUP62 (Ala186-Lys432). | ||||||||
| Cible | Nuclear pore glycoprotein p62, Nucleoporin Nup62, 62 kDa nucleoporin, NUP62 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P37198 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Nuclear pore glycoprotein p62 (NUP62) is a ~53 kDa protein. Essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex. Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation. It might be involved in protein recruitment to the centrosome after nuclear breakdown. 1. Carmo-Fonseca, M. et al. (1991) European journal of cell biology 55, 17-30. PMID: 1915414 2. Hashizume, C. et al. (2013) Cell cycle (Georgetown, Tex.) 12, 3804-16. PMID: 24107630 | ||||||||
| Note | For research use only. |
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