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Anti-OPG199 Polyclonal Antibody (VK070014)

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Número de catálogoVK070014
MarcaabinScience
Descripción
Anti-OPG199 Polyclonal Antibody (VK070014) is a rabbit polyclonal antibody detecting OPG199 in ELISA, IHC, WB. Suitable for Variola virus, Cowpox virus, Rabbitpox virus, Monkeypox virus, and Vaccinia virus.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesVariola virus, Cowpox virus, Rabbitpox virus, Monkeypox virus, Vaccinia virus
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant cpxv OPG199 (Met1-Leu300).
Objetivo CrmA or CPXV207 protein, CrmA
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso P07385, A0A7H0DNF9, P42926, P0DSW4, P20842, P15059, P0DSW3, P20841
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

Serine proteinase inhibitor 2 (OPG199) is a ~38 kDa protein. Viral serpin that inhibits both cysteine and serine proteinases involved in the regulation of host inflammatory and apoptosis processes. Major anti-apoptotic protein which inhibits both intrinsic and extrinsic pathways and strongly cleaves host CASP1 and CASP8 but is a rather poor inhibitor of host CASP3. Prevents the proteolytic activity of host interleukin-1-beta converting enzyme (ICE) and ICE-like enzymes. Can also block apoptosis through host tumor necrosis factor (TNF) receptor.

1. Simonovic, M. et al. (2000) Protein science : a publication of the Protein Society 9, 1423-7. PMID: 10975564
2. Renatus, M. et al. (2000) Structure (London, England : 1993) 8, 789-97. PMID: 10903953
Nota For research use only
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Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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