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| カタログ番号 | VK070014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| ブランド | abinScience | ||||||||
| 説明 |
Anti-OPG199 Polyclonal Antibody (VK070014) is a rabbit polyclonal antibody detecting OPG199 in ELISA, IHC, WB. Suitable for Variola virus, Cowpox virus, Rabbitpox virus, Monkeypox virus, and Vaccinia virus.
Highlights
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| 種反応性 | Variola virus, Cowpox virus, Rabbitpox virus, Monkeypox virus, Vaccinia virus | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant cpxv OPG199 (Met1-Leu300). | ||||||||
| ターゲット | CrmA or CPXV207 protein, CrmA | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P07385, A0A7H0DNF9, P42926, P0DSW4, P20842, P15059, P0DSW3, P20841 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Serine proteinase inhibitor 2 (OPG199) is a ~38 kDa protein. Viral serpin that inhibits both cysteine and serine proteinases involved in the regulation of host inflammatory and apoptosis processes. Major anti-apoptotic protein which inhibits both intrinsic and extrinsic pathways and strongly cleaves host CASP1 and CASP8 but is a rather poor inhibitor of host CASP3. Prevents the proteolytic activity of host interleukin-1-beta converting enzyme (ICE) and ICE-like enzymes. Can also block apoptosis through host tumor necrosis factor (TNF) receptor. 1. Simonovic, M. et al. (2000) Protein science : a publication of the Protein Society 9, 1423-7. PMID: 10975564 2. Renatus, M. et al. (2000) Structure (London, England : 1993) 8, 789-97. PMID: 10903953 | ||||||||
| 注意事項 | For research use only |
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