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Каталожный номерVK070014
БрендabinScience
Описание
Anti-OPG199 Polyclonal Antibody (VK070014) is a rabbit polyclonal antibody detecting OPG199 in ELISA, IHC, WB. Suitable for Variola virus, Cowpox virus, Rabbitpox virus, Monkeypox virus, and Vaccinia virus.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Реактивность видовVariola virus, Cowpox virus, Rabbitpox virus, Monkeypox virus, Vaccinia virus
ПримененияELISA, IHC, WB
Хозяинский видRabbit
КлоональностьPolyclonal
ИзотипIgG
Иммуноген E. coli - derived recombinant cpxv OPG199 (Met1-Leu300).
Цель CrmA or CPXV207 protein, CrmA
Уровень эндотоксинов Please contact with the lab for this information.
Очистка Purified by antigen affinity column.
Номер доступа P07385, A0A7H0DNF9, P42926, P0DSW4, P20842, P15059, P0DSW3, P20841
Форма Liquid
Буфер хранения 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта
Применение Разбавление
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Устойчивость и хранение Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон

Serine proteinase inhibitor 2 (OPG199) is a ~38 kDa protein. Viral serpin that inhibits both cysteine and serine proteinases involved in the regulation of host inflammatory and apoptosis processes. Major anti-apoptotic protein which inhibits both intrinsic and extrinsic pathways and strongly cleaves host CASP1 and CASP8 but is a rather poor inhibitor of host CASP3. Prevents the proteolytic activity of host interleukin-1-beta converting enzyme (ICE) and ICE-like enzymes. Can also block apoptosis through host tumor necrosis factor (TNF) receptor.

1. Simonovic, M. et al. (2000) Protein science : a publication of the Protein Society 9, 1423-7. PMID: 10975564
2. Renatus, M. et al. (2000) Structure (London, England : 1993) 8, 789-97. PMID: 10903953
Примечание For research use only
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Ссылки
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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