Anti-ORF7a/Protein U122 Polyclonal Antibody (VK586014)

Name: Anti-ORF7a/Protein U122 Polyclonal Antibody
Brand: abinScience
SKU: VK586014
Price: 168 USD
Availability: InStock

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Especificación:

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Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

VK586014

Descripción

Anti-ORF7a/Protein U122 Polyclonal Antibody (VK586014) is a rabbit polyclonal antibody detecting ORF7a protein in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant SARS-CoV-2 ORF7a/Protein U122 (Glu16-Tyr97).

Objetivo

ORF7a protein, ORF7a, Accessory protein 7a, Protein U122, Protein X4, 7a

Purificación

Purified by antigen affinity column.

Número de acceso

P0DTC7

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

ORF7a protein (Protein U122) is a ~13 kDa protein. Plays a role as antagonist of host tetherin (BST2), disrupting its antiviral effect. Acts by binding to BST2 and sequestering it to perinuclear region, thereby preventing its antiviral function at cell membrane. May specifically downregulate MHC-I allele HLA-A*02:01 (HLA-A2).

1. Martin-Sancho, L. et al. (2021) Molecular cell 81, 2656-2668.e8. PMID: 33930332

2. Arshad, N. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2208525120. PMID: 36574644

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-ORF7a/Protein U122 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo