Anti-ORF7a/Protein U122 Polyclonal Antibody (VK586014)

Name: Anti-ORF7a/Protein U122 Polyclonal Antibody
Brand: abinScience
SKU: VK586014
Price: 168 USD
Availability: InStock

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

VK586014

Description

Anti-ORF7a/Protein U122 Polyclonal Antibody (VK586014) is a rabbit polyclonal antibody detecting ORF7a protein in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant SARS-CoV-2 ORF7a/Protein U122 (Glu16-Tyr97).

Cible

ORF7a protein, ORF7a, Accessory protein 7a, Protein U122, Protein X4, 7a

Purification

Purified by antigen affinity column.

Numéro d'accès

P0DTC7

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

ORF7a protein (Protein U122) is a ~13 kDa protein. Plays a role as antagonist of host tetherin (BST2), disrupting its antiviral effect. Acts by binding to BST2 and sequestering it to perinuclear region, thereby preventing its antiviral function at cell membrane. May specifically downregulate MHC-I allele HLA-A*02:01 (HLA-A2).

1. Martin-Sancho, L. et al. (2021) Molecular cell 81, 2656-2668.e8. PMID: 33930332

2. Arshad, N. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2208525120. PMID: 36574644

Note

For research use only.

Images

Reférences

Fiche technique

Anti-ORF7a/Protein U122 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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