中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | VK586014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-ORF7a/Protein U122 Polyclonal Antibody (VK586014) is a rabbit polyclonal antibody detecting ORF7a protein in ELISA, IHC, WB.
Highlights
|
||||||||
| 種反応性 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant SARS-CoV-2 ORF7a/Protein U122 (Glu16-Tyr97). | ||||||||
| ターゲット | ORF7a protein, ORF7a, Accessory protein 7a, Protein U122, Protein X4, 7a | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P0DTC7 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||||
| 製品使用情報 |
| ||||||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | ORF7a protein (Protein U122) is a ~13 kDa protein. Plays a role as antagonist of host tetherin (BST2), disrupting its antiviral effect. Acts by binding to BST2 and sequestering it to perinuclear region, thereby preventing its antiviral function at cell membrane. May specifically downregulate MHC-I allele HLA-A*02:01 (HLA-A2). 1. Martin-Sancho, L. et al. (2021) Molecular cell 81, 2656-2668.e8. PMID: 33930332 2. Arshad, N. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2208525120. PMID: 36574644 | ||||||||
| 注意事項 | For research use only. |
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
