

| Numéro de catalogue | VK646034 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Orthohantavirus puumalaense Glycoprotein C/Gc Polyclonal Antibody (VK646034) is a rabbit polyclonal antibody detecting Glycoprotein N in ELISA, IHC, WB. Suitable for Puumala virus.
Highlights
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| Reactivité des espèces | Orthohantavirus puumalaense (Puumala virus) (PUUV) | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Orthohantavirus puumalaense Envelopment polyprotein (Glu659-Glu1105). | ||||||||
| Cible | Envelopment polyprotein, M polyprotein, Glycoprotein N, Glycoprotein C, Gc, Glycoprotein G2, GP | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | AJC50718.1 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Envelopment polyprotein (Glycoprotein C/Gc) is a ~125 kDa protein. Forms homotetramers with glycoprotein C at the surface of the virion. Attaches the virion to host cell receptors including integrin ITGAV/ITGB3. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Mediates the assembly and budding of infectious virus particles through its interaction with the nucleocapsid protein and the viral genome. May dysregulate normal immune and endothelial cell responses through an ITAM motif. | ||||||||
| Note | For research use only |




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