

| Numéro de catalogue | HY360014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Osteocalcin/BGLAP/OC Polyclonal Antibody (HY360014) is a rabbit polyclonal antibody detecting Osteocalcin in ELISA, IHC, WB. Suitable for Human, Dog, Ateles geoffroyi, Bison priscus, and Bovine.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human Osteocalcin/BGLAP/OC (Lys24-Val100). | ||||||||
| Cible | Gamma-carboxyglutamic acid-containing protein, BGLAP, BGP, Bone Gla protein, Osteocalcin | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P02818 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Osteocalcin (BGLAP) is a ~10 kDa protein. The carboxylated form is one of the main organic components of the bone matrix, which constitutes 1-2% of the total bone protein. Acts as a negative regulator of bone formation and is required to limit bone formation without impairing bone resorption or mineralization. Binds strongly to apatite and calcium upon gamma-carboxylation; this modification is essential for bone metabolism. 1. Celeste, AJ. et al. (1986) The EMBO journal 5, 1885-90. PMID: 3019668 2. Poser, JW. et al. (1980) The Journal of biological chemistry 255, 8685-91. PMID: 6967872 3. Wang, R. et al. (2025) Nature 639, 808-815. PMID: 39880952 | ||||||||
| Note | For research use only. |



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