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| カタログ番号 | HY360014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-Osteocalcin/BGLAP/OC Polyclonal Antibody (HY360014) is a rabbit polyclonal antibody detecting Osteocalcin in ELISA, IHC, WB. Suitable for Human, Dog, Ateles geoffroyi, Bison priscus, and Bovine.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human Osteocalcin/BGLAP/OC (Lys24-Val100). | ||||||||
| ターゲット | Gamma-carboxyglutamic acid-containing protein, BGLAP, BGP, Bone Gla protein, Osteocalcin | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P02818 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Osteocalcin (BGLAP) is a ~10 kDa protein. The carboxylated form is one of the main organic components of the bone matrix, which constitutes 1-2% of the total bone protein. Acts as a negative regulator of bone formation and is required to limit bone formation without impairing bone resorption or mineralization. Binds strongly to apatite and calcium upon gamma-carboxylation; this modification is essential for bone metabolism. 1. Celeste, AJ. et al. (1986) The EMBO journal 5, 1885-90. PMID: 3019668 2. Poser, JW. et al. (1980) The Journal of biological chemistry 255, 8685-91. PMID: 6967872 3. Wang, R. et al. (2025) Nature 639, 808-815. PMID: 39880952 | ||||||||
| 注意事項 | For research use only. |
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