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Anti-P2RX1 Polyclonal Antibody (HA787014)

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Vista general
Número de catálogoHA787014
Descripción
Anti-P2RX1 Polyclonal Antibody (HA787014) is a rabbit polyclonal antibody detecting P2X purinoceptor 1; P2X1; ATP receptor; Purinergic receptor; P2RX1; P2X1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant human P2RX1 (Gln56-Asp327).
Objetivo P2X purinoceptor 1; P2X1; ATP receptor; Purinergic receptor; P2RX1; P2X1
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso P51575, P51576, P47824
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

P2X purinoceptor 1 (P2RX1) is a ~44 kDa protein. ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and with relatively high calcium permeability. Furthermore, CTP functions as a weak affinity agonist for P2RX1. Plays a role a role in urogenital, immune and cardiovascular function. Specifically, plays an important role in neurogenic contraction of smooth muscle of the vas deferens, and therefore is essential for normal male reproductive function. In addition, contributes to smooth muscle contractions of the urinary bladder.

1. Bianchi, BR. et al. (1999) European journal of pharmacology 376, 127-38. PMID: 10440098
2. Egan, TM. et al. (2004) The Journal of neuroscience : the official journal of the Society for Neuroscience 24, 3413-20. PMID: 15056721
3. Allsopp, RC. et al. (2010) The Journal of biological chemistry 285, 32770-32777. PMID: 20699225
4. Valera, S. et al. (1995) Receptors & channels 3, 283-9. PMID: 8834001
5. Evans, RJ. et al. (1996) The Journal of physiology 497 ( Pt 2), 413-22. PMID: 8961184
6. Roberts, JA. et al. (2004) The Journal of biological chemistry 279, 9043-55. PMID: 14699168
7. Lecut, C. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 183, 2801-9. PMID: 19635923
Nota For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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