

| Каталожный номер | HA787014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-P2RX1 Polyclonal Antibody (HA787014) is a rabbit polyclonal antibody detecting P2X purinoceptor 1; P2X1; ATP receptor; Purinergic receptor; P2RX1; P2X1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| Реактивность видов | Human | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant human P2RX1 (Gln56-Asp327). | ||||||||
| Цель | P2X purinoceptor 1; P2X1; ATP receptor; Purinergic receptor; P2RX1; P2X1 | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P51575, P51576, P47824 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | P2X purinoceptor 1 (P2RX1) is a ~44 kDa protein. ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and with relatively high calcium permeability. Furthermore, CTP functions as a weak affinity agonist for P2RX1. Plays a role a role in urogenital, immune and cardiovascular function. Specifically, plays an important role in neurogenic contraction of smooth muscle of the vas deferens, and therefore is essential for normal male reproductive function. In addition, contributes to smooth muscle contractions of the urinary bladder. 1. Bianchi, BR. et al. (1999) European journal of pharmacology 376, 127-38. PMID: 10440098 2. Egan, TM. et al. (2004) The Journal of neuroscience : the official journal of the Society for Neuroscience 24, 3413-20. PMID: 15056721 3. Allsopp, RC. et al. (2010) The Journal of biological chemistry 285, 32770-32777. PMID: 20699225 4. Valera, S. et al. (1995) Receptors & channels 3, 283-9. PMID: 8834001 5. Evans, RJ. et al. (1996) The Journal of physiology 497 ( Pt 2), 413-22. PMID: 8961184 6. Roberts, JA. et al. (2004) The Journal of biological chemistry 279, 9043-55. PMID: 14699168 7. Lecut, C. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 183, 2801-9. PMID: 19635923 | ||||||||
| Примечание | For research use only |
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