

| Numéro de catalogue | HB482014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-PACC1 Polyclonal Antibody (HB482014) is a rabbit polyclonal antibody detecting Proton-activated chloride channel; PAC; hPAC; Acid-sensitive outwardly-rectifying anion channel; ASOR; Proton-activated outwardly rectifying anion channel; PAORAC; Transmembrane protein 206; hTMEM206; PACC1; C1orf75; TMEM206 in ELISA, IHC, WB. Suitable for Human, Bovine, Rat, and Mouse.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant human PACC1 (His98-Ala301). | ||||||||
| Cible | Proton-activated chloride channel; PAC; hPAC; Acid-sensitive outwardly-rectifying anion channel; ASOR; Proton-activated outwardly rectifying anion channel; PAORAC; Transmembrane protein 206; hTMEM206; PACC1; C1orf75; TMEM206 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9H813, Q2KHV2, Q66H28, Q9D771 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Proton-activated chloride channel (PACC1) is a ~40 kDa protein. Chloride channel gated by pH that facilitates the entry of chloride ions into cells upon exposure to extracellular acidic pH. Involved in acidosis-induced cell death by mediating chloride influx and subsequent cell swelling. 1. Yang, J. et al. (2019) Science (New York, N.Y.) 364, 395-399. PMID: 31023925 2. Ullrich, F. et al. (2019) eLife 8. PMID: 31318332 | ||||||||
| Note | For research use only |
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