

| Numéro de catalogue | HW310063 | ||||
|---|---|---|---|---|---|
| Reactivité des espèces | Human | ||||
| Applications | ELISA, FACS, Functional assay | ||||
| Espèce hôte | Human | ||||
| Clonalité | Monoclonal | ||||
| Isotype | IgG1, kappa | ||||
| ID de clone | HS20 | ||||
| Cible | pan-Glypican, heparan sulfate, Glypican-1, Secreted glypican-1, GPC1, Glypican-2, Secreted glypican-2, GPC2, Glypican-3, GTR2-2, Intestinal protein OCI-5, MXR7, Glypican-3 alpha subunit, Glypican-3 beta subunit, GPC3, OCI5, Glypican-4, K-glypican, Secreted glypican-4, GPC4, Glypican-5, Secreted glypican-5, GPC5, Glypican-6, Secreted glypican-6, GPC6 | ||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||
| Pureté | >95% as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Numéro d'accès | P35052, Q8N158, I6QTG3, O75487, P78333, Q9Y625 | ||||
| Forme | Liquid | ||||
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Contexte | Glypican-1 (pan-Glypican) is a ~61 kDa protein. Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination. May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling. | ||||
| Note | For research use only | ||||
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |

SDS-PAGE for Anti-pan-Glypican Antibody (HS20)
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