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| カタログ番号 | HX973033 | ||||
|---|---|---|---|---|---|
| 種反応性 | Drosophila melanogaster (Fruit fly) | ||||
| アプリケーション | IHC, IP, WB | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG1, kappa | ||||
| クローンID | K28/86 | ||||
| ターゲット | PSD-95, PSD95, Disks large homolog 4, Synapse-associated protein 90, DLG4, Postsynaptic density protein 95, SAP-90, SAP90 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | P78352 | ||||
| RRID | Anti-pan-MAGUK Antibody (K28/86) (abinScience Cat# HX973033, RRID:AB_3727042) |
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| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Disks large homolog 4 (Membrane-associated guanylate kinases (MAGUK)) is a ~80 kDa protein. Postsynaptic scaffolding protein that plays a critical role in synaptogenesis and synaptic plasticity by providing a platform for the postsynaptic clustering of crucial synaptic proteins. Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. 1. Brigidi, GS. et al. (2015) Nature communications 6, 8200. PMID: 26334723 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-pan-MAGUK Antibody (K28/86)
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