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Anti-Panitumumab Polyclonal Antibody (AF004024)

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概要
カタログ番号AF004024
説明
Anti-Panitumumab Polyclonal Antibody (AF004024) is a rabbit polyclonal antibody detecting Panitumumab in ELISA.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
種反応性General
アプリケーションELISA
宿主種Rabbit
クローン性Polyclonal
アイソタイプIgG
免疫原 Panitumumab
ターゲット Rabbit polyclonal to Vectibix.
特異性 The product is specific for Panitumumab. This antibody serves as an excellent positive control for Panitumumabb immunogenicity (ADA) assays.
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
精製 Purified by antigen affinity column.
アクセッション番号 CAS: 339177-26-3
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報
アプリケーション 希釈
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景Panitumumab with trade name Vectibix, is an FDA-approved drug for the treatment of patients with EGFR-expressing metastatic colorectal carcinoma with non-mutated (wild-type) KRAS after failure of fluoropyrimidine-, oxaliplatin- and irinotecan-containing chemotherapy regimens. It is a human monoclonal antibody. Panitumumab binds to the human EGF receptor (EGFR), preventing binding of activating ligands, such as the EGF and transforming growth factor-α. Antibodysystem Anti-Panitumumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Panitumumab.
• Multiplexed evaluation of a cell-based assay for the detection of antidrug neutralizing antibodies to panitumumab in human serum using automated fluorescent microscopy., PMID:20508254
注意事項 For research use only.
イメージ
参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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