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| カタログ番号 | HB323014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-PCBD1 Polyclonal Antibody (HB323014) is a rabbit polyclonal antibody detecting Pterin-4-alpha-carbinolamine dehydratase; PHS; 4.2.1.96; 4-alpha-hydroxy-tetrahydropterin dehydratase; Dimerization cofactor of hepatocyte nuclear factor 1-alpha; DCoH; Dimerization cofactor of HNF1; Phenylalanine hydroxylase-stimulating protein; Pterin carbinolamine dehydratase; PCD; PCBD1; DCOH; PCBD in ELISA, IHC, WB. Suitable for Human, Rat, Bovine, Mouse, and Chicken.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant human PCBD1 (Met1-Thr104). | ||||||||
| ターゲット | Pterin-4-alpha-carbinolamine dehydratase; PHS; 4.2.1.96; 4-alpha-hydroxy-tetrahydropterin dehydratase; Dimerization cofactor of hepatocyte nuclear factor 1-alpha; DCoH; Dimerization cofactor of HNF1; Phenylalanine hydroxylase-stimulating protein; Pterin carbinolamine dehydratase; PCD; PCBD1; DCOH; PCBD | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P61457, P61459, Q3ZBD3, P61458, O73930, Q91901 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Pterin-4-alpha-carbinolamine dehydratase (PCBD1) is a ~12 kDa protein. Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity. Also acts as a coactivator for HNF1B-dependent transcription. 1. Ferrè, S. et al. (2014) Journal of the American Society of Nephrology : JASN 25, 574-86. PMID: 24204001 | ||||||||
| 注意事項 | For research use only |
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