

| Numéro de catalogue | HC630014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-PCLAF Polyclonal Antibody (HC630014) is a rabbit polyclonal antibody detecting PCLAF in ELISA, IHC, WB. Suitable for Human, Rat, and Bovine.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human PCLAF (Met1-Glu111). | ||||||||
| Cible | PAF, Overexpressed in anaplastic thyroid carcinoma 1, PCNA-associated factor of 15 kDa, PCLAF, Hepatitis C virus NS5A-transactivated protein 9, PCNA-associated factor, OEATC-1, PCNA-clamp-associated factor, PAF15, HCV NS5A-transactivated protein 9, p15PAF, NS5ATP9, KIAA0101 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q15004 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | PCNA-associated factor (PCLAF) is a ~11 kDa protein. PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number. | ||||||||
| Note | For research use only. |
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