中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HY442014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-PDHB Polyclonal Antibody (HY442014) is a rabbit polyclonal antibody detecting PDHB in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pongo abelii.
Highlights
|
||||||||
| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PDHB (Leu31-Asn341). | ||||||||
| ターゲット | PDHB, PDHE1-B, PHE1B, Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P11177 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||||
| 製品使用情報 |
| ||||||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) is a ~39 kDa protein. Together with PDHA1 forms the heterotetrameric E1 subunit of the pyruvate dehydrogenase (PDH) complex. The PDH complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links cytoplasmic glycolysis and the mitochondrial tricarboxylic acid (TCA) cycle (Probable). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and dihydrolipoamide dehydrogenase (E3) (Probable). The E1 subunit catalyzes both the thiamine pyrophosphate (TPP)-dependent decarboxylation of pyruvate and the reductive acetylation of a lipoyl group covalently linked to the lipoyl-bearing domains of E2. 1. Seifert, F. et al. (2007) Biochemistry 46, 6277-87. PMID: 17474719 2. Kato, M. et al. (2008) Structure (London, England : 1993) 16, 1849-59. PMID: 19081061 | ||||||||
| 注意事項 | For research use only. |
お問い合わせ
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
