Anti-PDLIM4 Polyclonal Antibody (HA712014)

Name: Anti-PDLIM4 Polyclonal Antibody
Brand: abinScience
SKU: HA712014
Price: 168 USD
Availability: InStock

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Спецификация:

50ug
100ug

Количество:

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Обзор

Каталожный номер

HA712014

Описание

Anti-PDLIM4 Polyclonal Antibody (HA712014) is a rabbit polyclonal antibody detecting PDZ and LIM domain protein 4; LIM protein RIL; Reversion-induced LIM protein; PDLIM4; RIL in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant human PDLIM4 (Pro2-Glu84).

Цель

PDZ and LIM domain protein 4; LIM protein RIL; Reversion-induced LIM protein; PDLIM4; RIL

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

P50479, P70271, P36202, Q3T005

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

PDZ and LIM domain protein 4 (PDLIM4) is a ~35 kDa protein. Suppresses SRC activation by recognizing and binding to active SRC and facilitating PTPN13-mediated dephosphorylation of SRC 'Tyr-419' leading to its inactivation. Inactivated SRC dissociates from this protein allowing the initiation of a new SRC inactivation cycle. Involved in reorganization of the actin cytoskeleton. In nonmuscle cells, binds to ACTN1 (alpha-actinin-1), increases the affinity of ACTN1 to F-actin (filamentous actin), and promotes formation of actin stress fibers. Involved in regulation of the synaptic AMPA receptor transport in dendritic spines of hippocampal pyramidal neurons directing the receptors toward an insertion at the postsynaptic membrane.

1. Zhang, Y. et al. (2009) The Journal of cell biology 184, 785-92. PMID: 19307596

2. Guryanova, OA. et al. (2011) The Journal of biological chemistry 286, 26849-59. PMID: 21636573

Примечание

For research use only

Изображения

Western blot

Lane 1: A431 cell lysate
Lane 2: K562 cell lysate
Lane 3: Mouse brain lysate
Lane 4: Rat brain lysate

Ссылки

Даташит

Anti-PDLIM4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-PDLIM4 Polyclonal Antibody (HA712014)

Обзор

Изображения

Ссылки

Даташит

SDS