Anti-PEDV Spike glycoprotein S1 Polyclonal Antibody (VK564054)

Name: Anti-PEDV Spike glycoprotein S1 Polyclonal Antibody
Brand: abinScience
SKU: VK564054
Price: 168 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

VK564054

Descripción

Anti-PEDV S1/Spike glycoprotein 1 Polyclonal Antibody (VK564054) is a rabbit polyclonal antibody detecting Spike glycoprotein in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactividad de especies

Porcine epidemic diarrhea virus (PEDV)

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant PEDV S1/Spike glycoprotein 1 (Gln21-Glu496).

Aplicaciones probadas

Objetivo

Spike glycoprotein, S glycoprotein, E2, Peplomer protein, S, Porcine epidemic diarrhea virus, PEDV

Purificación

Purified by antigen affinity column.

Número de acceso

S0AP48

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Spike glycoprotein (S1/Spike glycoprotein 1) is a ~151 kDa protein. S1 region attaches the virion to the cell membrane by interacting with the host receptor, initiating the infection. Binding to the receptor probably induces conformational changes in the S glycoprotein unmasking the fusion peptide of S2 region and activating membranes fusion. S2 region belongs to the class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.

Nota

For research use only.

Imágenes

Western blot

Western blot analysis was performed using anti-S1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant PEDV S1/Spike glycoprotein 1 (Catalog No: VK564012)

Referencias

Datasheet