Anti-PEDV Spike glycoprotein S2 Polyclonal Antibody (VK564064)

Name: Anti-PEDV Spike glycoprotein S2 Polyclonal Antibody
Brand: abinScience
SKU: VK564064
Price: 168 USD
Availability: InStock

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100ug

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SDS

Обзор

Каталожный номер

VK564064

Описание

Anti-PEDV S2/Spike glycoprotein 2 Polyclonal Antibody (VK564064) is a rabbit polyclonal antibody detecting Spike glycoprotein in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Porcine epidemic diarrhea virus (PEDV)

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant PEDV S2/Spike glycoprotein 2 (Met961-Gln1386).

Проверенные приложения

Цель

Spike glycoprotein, S glycoprotein, E2, Peplomer protein, S, Porcine epidemic diarrhea virus, PEDV

Очистка

Purified by antigen affinity column.

Номер доступа

S0AP48

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Spike glycoprotein (S2/Spike glycoprotein 2) is a ~151 kDa protein. S1 region attaches the virion to the cell membrane by interacting with the host receptor, initiating the infection. Binding to the receptor probably induces conformational changes in the S glycoprotein unmasking the fusion peptide of S2 region and activating membranes fusion. S2 region belongs to the class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain.

Примечание

For research use only.

Изображения

Western blot

Western blot analysis was performed using anti-S2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant PEDV S2/Spike glycoprotein 2 (Catalog No: VK564022)

Ссылки

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