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| カタログ番号 | VK564074 | ||||||||
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| 説明 |
Anti-PEDV Spike Glycoprotein S2 Polyclonal Antibody (VK564074) is a rabbit polyclonal antibody detecting Spike glycoprotein. Suitable for Porcine epidemic diarrhea virus.
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| 種反応性 | Porcine epidemic diarrhea virus (PEDV) | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant PEDV Spike Glycoprotein S2 (Gly777-Val1120). | ||||||||
| テスト済みアプリケーション | WB | ||||||||
| ターゲット | E2, Peplomer protein, S, S glycoprotein, Spike glycoprotein | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q91AV1 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 背景 | Spike glycoprotein (Spike Glycoprotein S2) is a ~151 kDa protein. S1 region attaches the virion to the cell membrane by interacting with host ANPEP/aminopeptidase N, initiating the infection. Binding to the receptor probably induces conformational changes in the S glycoprotein unmasking the fusion peptide of S2 region and activating membranes fusion. S2 region belongs to the class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. | ||||||||
| 注意事項 | For research use only |
Lane 1: recombinant PEDV Spike Glycoprotein S2, N-His (Catalog No: VK564052)
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