Anti-Phospho-KCNB1 (pS563) Recombinant Antibody (L83/11R) (RC581013)

Name: Anti-Phospho-KCNB1 (pS563) Recombinant Antibody (L83/11R)
Brand: abinScience
SKU: RC581013
Price: 191 USD
Availability: InStock

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Precio(USD):

Especificación:

50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

RC581013

Reactividad de especies

Rat

Aplicaciones

IHC, IP, WB

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a, kappa

ID de clon

L83/11R

Objetivo

h-DRK1, Delayed rectifier potassium channel 1, Potassium voltage-gated channel subfamily B member 1, KCNB1, Voltage-gated potassium channel subunit Kv2.1, DRK1

Nivel de endotoxinas

< 10 EU/mg

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P15387

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Potassium voltage-gated channel subfamily B member 1 (p-KCNB1) is a ~95 kDa protein. Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in the pancreas and cardiovascular system. Contributes to the regulation of the action potential (AP) repolarization, duration and frequency of repetitive AP firing in neurons, muscle cells and endocrine cells and plays a role in homeostatic attenuation of electrical excitability throughout the brain. Also plays a role in the regulation of exocytosis independently of its electrical function. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane.

1. Murakoshi, H. et al. (1999) The Journal of neuroscience : the official journal of the Society for Neuroscience 19, 1728-35. PMID: 10024359

2. Du, J. et al. (2000) The Journal of physiology 522 Pt 1, 19-31. PMID: 10618149

3. Malin, SA. et al. (2002) The Journal of neuroscience : the official journal of the Society for Neuroscience 22, 10094-105. PMID: 12451110

4. Guan, D. et al. (2007) The Journal of physiology 581, 941-60. PMID: 17379638

5. Mohapatra, DP. et al. (2009) Channels (Austin, Tex.) 3, 46-56. PMID: 19276663

6. Guan, D. et al. (2013) The Journal of physiology 591, 4807-25. PMID: 23878373

7. Feinshreiber, L. et al. (2010) Journal of cell science 123, 1940-7. PMID: 20484665

8. Ju, M. et al. (2003) The Journal of biological chemistry 278, 12769-78. PMID: 12560340

9. Taglialatela, M. et al. (1991) Molecular pharmacology 40, 299-307. PMID: 1875913

10. VanDongen, AM. et al. (1990) Neuron 5, 433-43. PMID: 2206531

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Phospho-KCNB1 (pS563) Antibody (L83/11R)

Referencias

Datasheet

Anti-Phospho-KCNB1 (pS563) Recombinant Antibody (L83/11R).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo