Anti-Phospho-KCNB1 (pS563) Recombinant Antibody (L83/11R) (RC581013)

Name: Anti-Phospho-KCNB1 (pS563) Recombinant Antibody (L83/11R)
Brand: abinScience
SKU: RC581013
Price: 191 USD
Availability: InStock

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Spécification :

50ug
100ug
1mg

Nombre :

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

RC581013

Reactivité des espèces

Rat

Applications

IHC, IP, WB

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

L83/11R

Cible

h-DRK1, Delayed rectifier potassium channel 1, Potassium voltage-gated channel subfamily B member 1, KCNB1, Voltage-gated potassium channel subunit Kv2.1, DRK1

Niveau d'endotoxines

< 10 EU/mg

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P15387

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Potassium voltage-gated channel subfamily B member 1 (p-KCNB1) is a ~95 kDa protein. Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in the pancreas and cardiovascular system. Contributes to the regulation of the action potential (AP) repolarization, duration and frequency of repetitive AP firing in neurons, muscle cells and endocrine cells and plays a role in homeostatic attenuation of electrical excitability throughout the brain. Also plays a role in the regulation of exocytosis independently of its electrical function. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane.

1. Murakoshi, H. et al. (1999) The Journal of neuroscience : the official journal of the Society for Neuroscience 19, 1728-35. PMID: 10024359

2. Du, J. et al. (2000) The Journal of physiology 522 Pt 1, 19-31. PMID: 10618149

3. Malin, SA. et al. (2002) The Journal of neuroscience : the official journal of the Society for Neuroscience 22, 10094-105. PMID: 12451110

4. Guan, D. et al. (2007) The Journal of physiology 581, 941-60. PMID: 17379638

5. Mohapatra, DP. et al. (2009) Channels (Austin, Tex.) 3, 46-56. PMID: 19276663

6. Guan, D. et al. (2013) The Journal of physiology 591, 4807-25. PMID: 23878373

7. Feinshreiber, L. et al. (2010) Journal of cell science 123, 1940-7. PMID: 20484665

8. Ju, M. et al. (2003) The Journal of biological chemistry 278, 12769-78. PMID: 12560340

9. Taglialatela, M. et al. (1991) Molecular pharmacology 40, 299-307. PMID: 1875913

10. VanDongen, AM. et al. (1990) Neuron 5, 433-43. PMID: 2206531

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Phospho-KCNB1 (pS563) Antibody (L83/11R)

Reférences

Fiche technique

Anti-Phospho-KCNB1 (pS563) Recombinant Antibody (L83/11R).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

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