Anti-Phospho-KCNB1 (pS563) Recombinant Antibody (L83/11R) (RC581013)

Name: Anti-Phospho-KCNB1 (pS563) Recombinant Antibody (L83/11R)
Brand: abinScience
SKU: RC581013
Price: 191 USD
Availability: InStock

Даташит Поделиться продуктом Копировать информацию

Цена(USD):

Спецификация:

50ug
100ug
1mg

Количество:

Свяжитесь с нами

Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

RC581013

Реактивность видов

Rat

Применения

IHC, IP, WB

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG2a, kappa

ID клона

L83/11R

Цель

h-DRK1, Delayed rectifier potassium channel 1, Potassium voltage-gated channel subfamily B member 1, KCNB1, Voltage-gated potassium channel subunit Kv2.1, DRK1

Уровень эндотоксинов

< 10 EU/mg

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

P15387

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Potassium voltage-gated channel subfamily B member 1 (p-KCNB1) is a ~95 kDa protein. Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in the pancreas and cardiovascular system. Contributes to the regulation of the action potential (AP) repolarization, duration and frequency of repetitive AP firing in neurons, muscle cells and endocrine cells and plays a role in homeostatic attenuation of electrical excitability throughout the brain. Also plays a role in the regulation of exocytosis independently of its electrical function. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane.

1. Murakoshi, H. et al. (1999) The Journal of neuroscience : the official journal of the Society for Neuroscience 19, 1728-35. PMID: 10024359

2. Du, J. et al. (2000) The Journal of physiology 522 Pt 1, 19-31. PMID: 10618149

3. Malin, SA. et al. (2002) The Journal of neuroscience : the official journal of the Society for Neuroscience 22, 10094-105. PMID: 12451110

4. Guan, D. et al. (2007) The Journal of physiology 581, 941-60. PMID: 17379638

5. Mohapatra, DP. et al. (2009) Channels (Austin, Tex.) 3, 46-56. PMID: 19276663

6. Guan, D. et al. (2013) The Journal of physiology 591, 4807-25. PMID: 23878373

7. Feinshreiber, L. et al. (2010) Journal of cell science 123, 1940-7. PMID: 20484665

8. Ju, M. et al. (2003) The Journal of biological chemistry 278, 12769-78. PMID: 12560340

9. Taglialatela, M. et al. (1991) Molecular pharmacology 40, 299-307. PMID: 1875913

10. VanDongen, AM. et al. (1990) Neuron 5, 433-43. PMID: 2206531

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Phospho-KCNB1 (pS563) Antibody (L83/11R)

Ссылки

Даташит

Anti-Phospho-KCNB1 (pS563) Recombinant Antibody (L83/11R).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа