Anti-Phospho-PLC-γ (pY783) Recombinant Antibody (SAA0303) (HB687013)

Name: Anti-Phospho-PLC-γ (pY783) Recombinant Antibody (SAA0303)
Brand: abinScience
SKU: HB687013
Price: 191 USD
Availability: InStock

Fiche technique Partager le produit Copier les informations

Prix(USD) :

Spécification :

50ug
100ug
1mg

Nombre :

Contactez-nous

Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HB687013

Reactivité des espèces

Human, Mouse

Applications

IHC, IP, WB

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA0303

Cible

Phosphoinositide phospholipase C-gamma-1, PLC1, PLC-II, Phospholipase C-II, Phospholipase C-gamma-1, PLC-gamma-1, PLC-148, PLCG1, 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase gamma-1

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P19174

RRID

Anti-Phospho-PLC-γ (pY783) Antibody (SAA0303) (abinScience Cat# HB687013, RRID:AB_3725764)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (p-PLC-γ) is a ~148 kDa protein. Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, EGFR, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration. Guanine nucleotide exchange factor that binds the GTPase DNM1 and catalyzes the dissociation of GDP, allowing a GTP molecule to bind in its place, therefore enhancing DNM1-dependent endocytosis.

1. Wang, Y. et al. (2007) American journal of physiology. Cell physiology 292, C1775-86. PMID: 17229814

Note

For research use only.

Images