中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | HB687013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human, Mouse | ||||
| アプリケーション | IHC, IP, WB | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA0303 | ||||
| ターゲット | Phosphoinositide phospholipase C-gamma-1, PLC1, PLC-II, Phospholipase C-II, Phospholipase C-gamma-1, PLC-gamma-1, PLC-148, PLCG1, 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase gamma-1 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | P19174 | ||||
| RRID | Anti-Phospho-PLC-γ (pY783) Antibody (SAA0303) (abinScience Cat# HB687013, RRID:AB_3725764) |
||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||
| 製品使用情報 |
| ||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (p-PLC-γ) is a ~148 kDa protein. Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, EGFR, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration. Guanine nucleotide exchange factor that binds the GTPase DNM1 and catalyzes the dissociation of GDP, allowing a GTP molecule to bind in its place, therefore enhancing DNM1-dependent endocytosis. 1. Wang, Y. et al. (2007) American journal of physiology. Cell physiology 292, C1775-86. PMID: 17229814 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Phospho-PLC-γ (pY783) Antibody (SAA0303)
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
