Anti-Phospho-STAT3 (pY705) Recombinant Antibody (SAA0302) (HW708013)

Name: Anti-Phospho-STAT3 (pY705) Recombinant Antibody (SAA0302)
Brand: abinScience
SKU: HW708013
Price: 126 USD
Availability: InStock

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Precio(USD):

Especificación:

20ug
50ug
100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HW708013

Reactividad de especies

Human, Mouse

Aplicaciones

ELISA, IP, WB

Especie huésped

Mouse

Clonalidad

Monoclonal

Isotipo

IgG2a, kappa

ID de clon

SAA0302

Objetivo

Signal transducer and activator of transcription 3, APRF, STAT3, Acute-phase response factor

Nivel de endotoxinas

Please contact with the lab for this information.

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P40763

RRID

Anti-Phospho-STAT3 (pY705) Antibody (SAA0302) (abinScience Cat# HW708013, RRID:AB_3725763)

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Fondo

Signal transducer and activator of transcription 3 (p-STAT3) is a ~88 kDa protein. Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Upon activation of IL6ST/gp130 signaling by interleukin-6 (IL6), binds to the IL6-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.

1. Tsai, YT. et al. (2000) Molecular and cellular biology 20, 2043-54. PMID: 10688651

2. Yamamoto, T. et al. (2002) Biochemical and biophysical research communications 297, 811-7. PMID: 12359225

3. Shao, H. et al. (2003) Cancer research 63, 3923-30. PMID: 12873986

4. Dreuw, A. et al. (2004) The Journal of biological chemistry 279, 36112-20. PMID: 15194700

5. Yuan, ZL. et al. (2005) Science (New York, N.Y.) 307, 269-73. PMID: 15653507

6. Ray, S. et al. (2005) Gastroenterology 129, 1616-32. PMID: 16285960

7. Saxena, NK. et al. (2007) The Journal of biological chemistry 282, 13316-25. PMID: 17344214

8. Jiang, H. et al. (2008) Biochemical and biophysical research communications 368, 1-5. PMID: 18242580

9. Hou, T. et al. (2008) The Journal of biological chemistry 283, 30725-34. PMID: 18782771

10. Gao, X. et al. (2012) Molecular cell 45, 598-609. PMID: 22306293

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for Anti-Phospho-STAT3 (pY705) Antibody (SAA0302)

Referencias

Datasheet

Anti-Phospho-STAT3 (pY705) Recombinant Antibody (SAA0302).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo