Anti-Phospho-STAT3 (pY705) Recombinant Antibody (SAA0302) (HW708013)

Name: Anti-Phospho-STAT3 (pY705) Recombinant Antibody (SAA0302)
Brand: abinScience
SKU: HW708013
Price: 126 USD
Availability: InStock

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Спецификация:

20ug
50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HW708013

Реактивность видов

Human, Mouse

Применения

ELISA, IP, WB

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG2a, kappa

ID клона

SAA0302

Цель

Signal transducer and activator of transcription 3, APRF, STAT3, Acute-phase response factor

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

P40763

RRID

Anti-Phospho-STAT3 (pY705) Antibody (SAA0302) (abinScience Cat# HW708013, RRID:AB_3725763)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Signal transducer and activator of transcription 3 (p-STAT3) is a ~88 kDa protein. Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Upon activation of IL6ST/gp130 signaling by interleukin-6 (IL6), binds to the IL6-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.

1. Tsai, YT. et al. (2000) Molecular and cellular biology 20, 2043-54. PMID: 10688651

2. Yamamoto, T. et al. (2002) Biochemical and biophysical research communications 297, 811-7. PMID: 12359225

3. Shao, H. et al. (2003) Cancer research 63, 3923-30. PMID: 12873986

4. Dreuw, A. et al. (2004) The Journal of biological chemistry 279, 36112-20. PMID: 15194700

5. Yuan, ZL. et al. (2005) Science (New York, N.Y.) 307, 269-73. PMID: 15653507

6. Ray, S. et al. (2005) Gastroenterology 129, 1616-32. PMID: 16285960

7. Saxena, NK. et al. (2007) The Journal of biological chemistry 282, 13316-25. PMID: 17344214

8. Jiang, H. et al. (2008) Biochemical and biophysical research communications 368, 1-5. PMID: 18242580

9. Hou, T. et al. (2008) The Journal of biological chemistry 283, 30725-34. PMID: 18782771

10. Gao, X. et al. (2012) Molecular cell 45, 598-609. PMID: 22306293

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Phospho-STAT3 (pY705) Antibody (SAA0302)

Ссылки

Даташит

Anti-Phospho-STAT3 (pY705) Recombinant Antibody (SAA0302).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

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