Anti-PIK3C3 Polyclonal Antibody (HV616014)

Name: Anti-PIK3C3 Polyclonal Antibody
Brand: abinScience
SKU: HV616014
Price: 168 USD
Availability: InStock

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Especificación:

50ug
100ug

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Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

HV616014

Descripción

Anti-PIK3C3 Polyclonal Antibody (HV616014) is a rabbit polyclonal antibody detecting PIK3C3 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Pig, and Xenopus laevis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Reactividad de especies

Human, Mouse, Rat

Aplicaciones

ELISA, IHC, WB

Especie huésped

Rabbit

Clonalidad

Polyclonal

Isotipo

IgG

Inmunógeno

E. coli - derived recombinant Human PIK3C3 (Tyr631-Trp885).

Objetivo

PtdIns-3-kinase type 3, Phosphatidylinositol 3-kinase p100 subunit, hVps34, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphoinositide-3-kinase class 3, PI3-kinase type 3, VPS34, PI3K type 3, PIK3C3

Purificación

Purified by antigen affinity column.

Número de acceso

Q8NEB9

Forma

Liquid

Buffer de almacenamiento

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Phosphatidylinositol 3-kinase catalytic subunit type 3 (PIK3C3) is a ~101 kDa protein. Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. As part of PI3KC3-C1, promotes endoplasmic reticulum membrane curvature formation prior to vesicle budding. Involved in regulation of degradative endocytic trafficking and required for the abscission step in cytokinesis, probably in the context of PI3KC3-C2. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes.

1. Stein, MP. et al. (2003) Traffic (Copenhagen, Denmark) 4, 754-71. PMID: 14617358

2. Chen, YH. et al. (2021) Nature communications 12, 1322. PMID: 33637724

3. Volinia, S. et al. (1995) The EMBO journal 14, 3339-48. PMID: 7628435

4. Zhang, BC. et al. (2020) Nature immunology 21, 868-879. PMID: 32690950

5. Sagona, AP. et al. (2010) Nature cell biology 12, 362-71. PMID: 20208530

6. Thoresen, SB. et al. (2010) Experimental cell research 316, 3368-78. PMID: 20643123

Nota

For research use only.

Imágenes

Referencias

Datasheet

Anti-PIK3C3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

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