

| Numéro de catalogue | HW552014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-PIK3CG Polyclonal Antibody (HW552014) is a rabbit polyclonal antibody detecting PIK3CG in ELISA, IHC, WB. Suitable for Human, Mouse, and Pig.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human PIK3CG (Lys298-Leu467). | ||||||||
| Cible | PtdIns-3-kinase subunit gamma, Phosphatidylinositol 4, 5-bisphosphate 3-kinase catalytic subunit gamma isoform, PtdIns-3-kinase subunit p110-gamma, PI3Kgamma, p120-PI3K, Phosphatidylinositol 4, 5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma, PI3-kinase subunit gamma, PI3K-gamma, Phosphoinositide-3-kinase catalytic gamma polypeptide, Serine/threonine protein kinase PIK3CG, p110gamma, PIK3CG | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P48736 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PIK3CG) is a ~126 kDa protein. Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Links G-protein coupled receptor activation to PIP3 production. Involved in immune, inflammatory and allergic responses. Modulates leukocyte chemotaxis to inflammatory sites and in response to chemoattractant agents. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-PIK3CG polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse spleen lysate
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