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| カタログ番号 | HW552014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-PIK3CG Polyclonal Antibody (HW552014) is a rabbit polyclonal antibody detecting PIK3CG in ELISA, IHC, WB. Suitable for Human, Mouse, and Pig.
Highlights
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| 種反応性 | Human, Mouse | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PIK3CG (Lys298-Leu467). | ||||||||
| ターゲット | PtdIns-3-kinase subunit gamma, Phosphatidylinositol 4, 5-bisphosphate 3-kinase catalytic subunit gamma isoform, PtdIns-3-kinase subunit p110-gamma, PI3Kgamma, p120-PI3K, Phosphatidylinositol 4, 5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma, PI3-kinase subunit gamma, PI3K-gamma, Phosphoinositide-3-kinase catalytic gamma polypeptide, Serine/threonine protein kinase PIK3CG, p110gamma, PIK3CG | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P48736 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PIK3CG) is a ~126 kDa protein. Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Links G-protein coupled receptor activation to PIP3 production. Involved in immune, inflammatory and allergic responses. Modulates leukocyte chemotaxis to inflammatory sites and in response to chemoattractant agents. | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-PIK3CG polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse spleen lysate
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