Anti-PLA2G6 Polyclonal Antibody (HT140014)

Name: Anti-PLA2G6 Polyclonal Antibody
Brand: abinScience
SKU: HT140014
Price: 168 USD
Availability: InStock

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Спецификация:

50ug
100ug

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HT140014

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human PLA2G6 (Asp484-Val701).

Цель

Patatin-like phospholipase domain-containing protein 9, Group VI phospholipase A2, iPLA2-beta, PLA2G6, PLPLA9, Intracellular membrane-associated calcium-independent phospholipase A2 beta, GVI PLA2, CaI-PLA2, Palmitoyl-CoA hydrolase, 2-lysophosphatidylcholine acylhydrolase, 85/88 kDa calcium-independent phospholipase A2, PNPLA9

Очистка

Purified by antigen affinity column.

Номер доступа

O60733

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

85/88 kDa calcium-independent phospholipase A2 (PLA2G6) is a ~89 kDa protein. Calcium-independent phospholipase involved in phospholipid remodeling with implications in cellular membrane homeostasis, mitochondrial integrity and signal transduction. Hydrolyzes the ester bond of the fatty acyl group attached at sn-1 or sn-2 position of phospholipids (phospholipase A1 and A2 activity respectively), producing lysophospholipids that are used in deacylation-reacylation cycles. Hydrolyzes both saturated and unsaturated long fatty acyl chains in various glycerophospholipid classes such as phosphatidylcholines, phosphatidylethanolamines and phosphatidates, with a preference for hydrolysis at sn-2 position. Can further hydrolyze lysophospholipids carrying saturated fatty acyl chains (lysophospholipase activity). Upon oxidative stress, contributes to remodeling of mitochondrial phospholipids in pancreatic beta cells, in a repair mechanism to reduce oxidized lipid content.

1. Ma, Z. et al. (1999) The Journal of biological chemistry 274, 9607-16. PMID: 10092647

2. Larsson Forsell, PK. et al. (1999) European journal of biochemistry 262, 575-85. PMID: 10336645

3. Engel, LA. et al. (2010) PloS one 5, e12897. PMID: 20886109

4. Larsson, PK. et al. (1998) The Journal of biological chemistry 273, 207-14. PMID: 9417066

5. Hsu, YH. et al. (2013) PloS one 8, e59267. PMID: 23533611

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-PLA2G6 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа