Anti-PLAA Polyclonal Antibody (HV798014)

Name: Anti-PLAA Polyclonal Antibody
Brand: abinScience
SKU: HV798014
Price: 168 USD
Availability: InStock

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Обзор

Каталожный номер

HV798014

Описание

Anti-PLAA Polyclonal Antibody (HV798014) is a rabbit polyclonal antibody detecting PLAA in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human PLAA (Glu162-Ala312).

Цель

PLAP, PLA2P, Phospholipase A-2-activating protein, PLAA

Очистка

Purified by antigen affinity column.

Номер доступа

Q9Y263

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

Phospholipase A-2-activating protein (PLAA) is a ~87 kDa protein. Plays a role in protein ubiquitination, sorting and degradation through its association with VCP. Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes. Plays a role in cerebellar Purkinje cell development. Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF)- or lipopolysaccharide (LPS)-dependent manner, and hence prostaglandin E2 biosynthesis.

1. Papadopoulos, C. et al. (2017) The EMBO journal 36, 135-150. PMID: 27753622

2. Zhang, F. et al. (2008) Cellular signalling 20, 844-61. PMID: 18291623

3. Falik Zaccai, TC. et al. (2017) Brain : a journal of neurology 140, 370-386. PMID: 28007986

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-PLAA Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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