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Anti-PLCB4 Polyclonal Antibody (HA808014)

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Aperçu
Numéro de catalogueHA808014
Description
Anti-PLCB4 Polyclonal Antibody (HA808014) is a rabbit polyclonal antibody detecting 5-bisphosphate phosphodiesterase beta-4; 3.1.4.11; Phosphoinositide phospholipase C-beta-4; Phospholipase C-beta-4; PLC-beta-4; PLCB4 in ELISA, IHC, WB. Suitable for Human, Bovine, and Rat.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
Reactivité des espècesHuman, Rat
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant human PLCB4 (Met1-Asn301).
Cible 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4; 3.1.4.11; Phosphoinositide phospholipase C-beta-4; Phospholipase C-beta-4; PLC-beta-4; PLCB4
Niveau d'endotoxines Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Numéro d'accès Q15147, Q07722, Q9QW07
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 (PLCB4) is a ~134 kDa protein. Activated phosphatidylinositol-specific phospholipase C enzymes catalyze the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) involved in G-protein coupled receptor signaling pathways. PLCB4 is a direct effector of the endothelin receptor signaling pathway that plays an essential role in lower jaw and middle ear structures development.

1. Kanai, SM. et al. (2022) Disease models & mechanisms 15. PMID: 35284927
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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