

| Numéro de catalogue | HV576014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-POMT1 Polyclonal Antibody (HV576014) is a rabbit polyclonal antibody detecting POMT1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human POMT1 (Pro318-His513). | ||||||||
| Cible | POMT1, Dolichyl-phosphate-mannose--protein mannosyltransferase 1, Protein O-mannosyl-transferase 1 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9Y6A1 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Protein O-mannosyl-transferase 1 (POMT1) is a ~84 kDa protein. Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient. Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins. 1. Beltrán-Valero de Bernabé, D. et al. (2002) American journal of human genetics 71, 1033-43. PMID: 12369018 2. Manya, H. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 500-5. PMID: 14699049 3. Larsen, ISB. et al. (2017) The Journal of biological chemistry 292, 11586-11598. PMID: 28512129 | ||||||||
| Note | For research use only. |
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