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| カタログ番号 | HV576014 | ||||||||
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| 説明 |
Anti-POMT1 Polyclonal Antibody (HV576014) is a rabbit polyclonal antibody detecting POMT1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human POMT1 (Pro318-His513). | ||||||||
| ターゲット | POMT1, Dolichyl-phosphate-mannose--protein mannosyltransferase 1, Protein O-mannosyl-transferase 1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q9Y6A1 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Protein O-mannosyl-transferase 1 (POMT1) is a ~84 kDa protein. Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient. Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins. 1. Beltrán-Valero de Bernabé, D. et al. (2002) American journal of human genetics 71, 1033-43. PMID: 12369018 2. Manya, H. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 500-5. PMID: 14699049 3. Larsen, ISB. et al. (2017) The Journal of biological chemistry 292, 11586-11598. PMID: 28512129 | ||||||||
| 注意事項 | For research use only. |
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