中文
English
한국어
日本語
Español
Français
Русский
| カタログ番号 | JN089014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 種反応性 | Porphyromonas gingivalis | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Porphyromonas gingivalis kgp/prtK (Asp229-Pro683). | ||||||||
| ターゲット | Lys-gingipain W83, 3.4.22.47, Lysine specific cysteine protease, Lysine-specific cysteine proteinase, Porphypain, PrtK48, Lys-gingipain catalytic subunit, 39 kDa adhesin, PrtK39, 15 kDa adhesin, PrtK15, 44 kDa adhesin, PrtK44, kgp, prtK, prtP | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q51817 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
||||||||
| 製品使用情報 |
| ||||||||
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Lys-gingipain W83 (kgp/prtK) is a ~187 kDa protein. Cysteine proteinase with a strong preference for substrates with Lys in the P1 position. Hydrolyzes bovine hemoglobin, bovine serum albumin, casein, human placental type I collagen and human IgA and IgG. Disrupts the functions of polymorphonuclear leukocytes. May act as a virulence factor in the development of peridontal disease. Involved in the coaggregation of P.gingivalis with other oral bacteria. 1. Bhogal, PS. et al. (1997) Microbiology (Reading, England) 143 ( Pt 7), 2485-2495. PMID: 9245829 2. Li, N. et al. (2011) Molecular microbiology 81, 1358-73. PMID: 21812842 3. Ganuelas, LA. et al. (2013) European journal of microbiology & immunology 3, 152-62. PMID: 24265933 | ||||||||
| 注意事項 | For research use only. |
Western blot analysis was performed using anti-Kgp polyclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant Porphyromonas gingivalis kgp/prtK (Catalog No: JN089012), 70 ug
Lane 2: recombinant Porphyromonas gingivalis kgp/prtK (Catalog No: JN089012), 50 ug
Lane 3: recombinant Porphyromonas gingivalis kgp/prtK (Catalog No: JN089012), 30 ug
Lane 4: recombinant Porphyromonas gingivalis kgp/prtK (Catalog No: JN089012), 10 ug
+86-027-65523339
中国武漢市深敦寺路666号C棟、武漢、430206
