

| Numéro de catalogue | HV182014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-PPIE Polyclonal Antibody (HV182014) is a rabbit polyclonal antibody detecting PPIE in ELISA, IHC, WB. Suitable for Bovine, Human, Mouse, and Pongo abelii.
Highlights
|
||||||||
| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human PPIE (Tyr41-Val264). | ||||||||
| Cible | Peptidyl-prolyl cis-trans isomerase E, PPIE, PPIase E, Cyclophilin-33, CYP33, Rotamase E, Cyclophilin E | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q9UNP9 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
||||||||
| Informations d'utilisation du produit |
| ||||||||
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Peptidyl-prolyl cis-trans isomerase E (PPIE) is a ~33 kDa protein. Involved in pre-mRNA splicing as component of the spliceosome. Combines RNA-binding and PPIase activities. Binds mRNA and has a preference for single-stranded RNA molecules with poly-A and poly-U stretches, suggesting it binds to the poly(A)-region in the 3'-UTR of mRNA molecules. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins. Inhibits KMT2A activity; this requires proline isomerase activity. 1. Jurica, MS. et al. (2002) RNA (New York, N.Y.) 8, 426-39. PMID: 11991638 2. Bertram, K. et al. (2017) Nature 542, 318-323. PMID: 28076346 3. Wang, Y. et al. (2008) FEBS letters 582, 835-9. PMID: 18258190 4. Hom, RA. et al. (2010) Journal of molecular biology 400, 145-54. PMID: 20460131 5. Park, S. et al. (2010) Biochemistry 49, 6576-86. PMID: 20677832 6. Mi, H. et al. (1996) FEBS letters 398, 201-5. PMID: 8977107 | ||||||||
| Note | For research use only. |
Contactez-nous pour les devis personnalisés, les demandes en gros et tout autre problème.
Courrier : [email protected]
Accès rapide
Contactez-nous
+86-027-65523339
Bâtiment C, No. 666, Rue Shendunsi, Wuhan, 430206, Chine
中文
English
한국어
日本語
Español
Français
Русский