

| Numéro de catalogue | HW659014 | ||||||||
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| Description |
Anti-PPM1A Polyclonal Antibody (HW659014) is a rabbit polyclonal antibody detecting PPM1A in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human PPM1A (Gly2-Trp382). | ||||||||
| Cible | Protein phosphatase 2C isoform alpha, PPPM1A, Protein phosphatase 1A, Protein phosphatase IA, PP2C-alpha, PPM1A | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P35813 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Protein phosphatase 1A (PPM1A) is a ~42 kDa protein. Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB. | ||||||||
| Note | For research use only. |
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