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| カタログ番号 | JN126014 | ||||||||
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| 説明 |
Anti-pptT Polyclonal Antibody (JN126014) is a rabbit polyclonal antibody detecting 4'-phosphopantetheinyl transferase PptT; PPTase; 2.7.8.7; pptT; Rv2794c in ELISA, IHC, WB.
Highlights
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| 種反応性 | Mycobacterium tuberculosis | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant pptT (Met1-Leu227). | ||||||||
| ターゲット | 4'-phosphopantetheinyl transferase PptT; PPTase; 2.7.8.7; pptT; Rv2794c | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O33336 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | 4'-phosphopantetheinyl transferase PptT is a ~24 kDa protein. Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. Involved in post-translational modification of various type-I polyketide synthases required for the formation of both mycolic acids and lipid virulence factors. Acts on Pks13, Mas, PpsA, PpsB, PpsC and PpsD. Also acts on AcpM, the meromycolate extension acyl carrier protein. In addition, is involved in the activation of the acyl carrier protein MbtL and the nonribosomal peptides synthases MbtB and MbtE, which are involved in the biosynthesis of the siderophore mycobactin. 1. Chalut, C. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 8511-6. PMID: 16709676 2. Zimhony, O. et al. (2015) Biochemistry 54, 2360-71. PMID: 25785780 3. Jung, J. et al. (2016) FEBS open bio 6, 1220-1226. PMID: 28203522 4. Quadri, LE. et al. (1998) Chemistry & biology 5, 631-45. PMID: 9831524 | ||||||||
| 注意事項 | For research use only |
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