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| カタログ番号 | HF653014 | ||||||||
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| 説明 |
Anti-PQBP1 Polyclonal Antibody (HF653014) is a rabbit polyclonal antibody detecting PQBP1 in ELISA, IHC, WB. Suitable for Bovine, Human, Mouse, Pongo pygmaeus, and Rat.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PQBP1 (Met1-Asp265). | ||||||||
| ターゲット | NPW38, PQBP1, Polyglutamine tract-binding protein 1, PQBP-1, Npw38, 38 kDa nuclear protein containing a WW domain, Polyglutamine-binding protein 1 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | O60828 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Polyglutamine-binding protein 1 (PQBP1) is a ~30 kDa protein. Intrinsically disordered protein that acts as a scaffold, and which is involved in different processes, such as pre-mRNA splicing, transcription regulation, innate immunity and neuron development. Interacts with splicing-related factors via the intrinsically disordered region and regulates alternative splicing of target pre-mRNA species. May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. 1. Komuro, A. et al. (1999) Nucleic acids research 27, 1957-65. PMID: 10198427 2. Waragai, M. et al. (1999) Human molecular genetics 8, 977-87. PMID: 10332029 3. Okazawa, H. et al. (2002) Neuron 34, 701-13. PMID: 12062018 4. Tapia, VE. et al. (2010) The Journal of biological chemistry 285, 19391-401. PMID: 20410308 5. Wang, Q. et al. (2013) Genes & development 27, 615-26. PMID: 23512658 | ||||||||
| 注意事項 | For research use only. |
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