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| カタログ番号 | HB236014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-PRDX3 Polyclonal Antibody (HB236014) is a rabbit polyclonal antibody detecting PRDX3 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pongo abelii.
Highlights
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| 種反応性 | Human | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human PRDX3 (Val5-Trp233). | ||||||||
| ターゲット | HBC189, AOP1, Antioxidant protein 1, Peroxiredoxin III, AOP-1, Protein MER5 homolog, Prx-III, Peroxiredoxin-3, Thioredoxin-dependent peroxide reductase, mitochondrial, Thioredoxin-dependent peroxiredoxin 3, PRDX3 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P30048 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Thioredoxin-dependent peroxide reductase, mitochondrial (PRDX3) is a ~27 kDa protein. Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. Required for the maintenance of physical strength. 1. Cao, Z. et al. (2007) Journal of molecular biology 372, 1022-1033. PMID: 17707404 2. Yewdall, NA. et al. (2018) Biochemical and biophysical research communications 497, 558-563. PMID: 29438714 3. Rebelo, AP. et al. (2021) Brain : a journal of neurology 144, 1467-1481. PMID: 33889951 4. Tsuji, K. et al. (1995) The Biochemical journal 307 ( Pt 2), 377-81. PMID: 7733872 5. Masaki, M. et al. (2003) European journal of biochemistry 270, 76-83. PMID: 12492477 | ||||||||
| 注意事項 | For research use only. |
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